Significantly, animals with very clear MDMX protein depletion showed simply no associated change in MDM2 (Fig.?2d). MDM2 and MDMX knockdown lower?cell migration in vitro for MDA-MB-231 cells We previously showed that inducible knockdown of MDM2 does not have any impact on MDA-MB-231 cell viability or proliferation [7]. 231.mir30.vector, 231.shor 231.shengrafted cells. Arrow factors to metastases. […]