´╗┐Each part of the CAR design, from the recognition domain to the ITAMs of CD3 can be optimized to enhance downstream signaling

´╗┐Each part of the CAR design, from the recognition domain to the ITAMs of CD3 can be optimized to enhance downstream signaling. of receptors and antigens, proximal signaling, immunological synapse formation, and late signaling outcomes. Signaling through different T cell subtypes and how signaling is translated into practice are also discussed. construct to the TCR […]

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