The LC-MS/MS assay was applied for DMB metabolic stability assessment with an RLM matrix, and the two parameters, (157.5 min) and (0.97 mL/min/kg), were calculated. linearity of the established LC-MS/MS assay ranged from 2 to 500 ng/mL with 0.9999. The limit of detection (t1/2 (0.97 mL/min/kg) and intrinsic clearance (157.5 min). Such values infer that […]