Consistent with prior observations, typhoid toxin made by wild-type Typhi caused cell distension and cell-cycle arrest in G2/M within a toxin dose-dependent way (Statistics 3AC3C), whose specificity was verified using an isogenic mutant Typhi-producing typhoid toxin carrying the catalytic-mutant CdtBH160Q subunit (STy CdtB mt) whose cell-cycle arrest profiles in G2/M was comparable with this of uninfected cells (Statistics 3AC3C)

Consistent with prior observations, typhoid toxin made by wild-type Typhi caused cell distension and cell-cycle arrest in G2/M within a toxin dose-dependent way (Statistics 3AC3C), whose specificity was verified using an isogenic mutant Typhi-producing typhoid toxin carrying the catalytic-mutant CdtBH160Q subunit (STy CdtB mt) whose cell-cycle arrest profiles in G2/M was comparable with this of […]

Western blots teaching ramifications of (a) BGT226, (b) BKM120 and (c) RAD001 dosage escalation about p-Ser473 Akt (p-Akt) and p-Ser235/236 S6 (p-S6) in breasts tumor cell lines

Western blots teaching ramifications of (a) BGT226, (b) BKM120 and (c) RAD001 dosage escalation about p-Ser473 Akt (p-Akt) and p-Ser235/236 S6 (p-S6) in breasts tumor cell lines. 51 recurrent or metastatic breast cancers and correlated with ER survival and position. Outcomes Drug-induced apoptosis was most marked in short-term estrogen-deprived cells with PIK3CA phosphatase and mutation […]

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