Jrgens, M. junctional protein had been quantified by RT-qPCR. Outcomes: Adoptive transfer of Compact disc4+Compact disc25?Compact disc62L+ T cells led to colonic inflammation and an altered intestinal permeability. The serine protease inhibitor UAMC-00050 ameliorated both inflammatory parameters as well as the intestinal hurdle function. Furthermore, a reduction in colonic mRNA manifestation of PAR4 and Tbet […]