These findings in C57BL/6J HRI( Collectively?/?) hepatocytes act like those obtained in MGB HRI( essentially?/?) hepatocytes and so are in keeping with HRI-mediated translational control of CYP3A and CYP2B induction by PB. Open in another window Fig. highly relevant to severe heme-deficient areas medically, like the severe hepatic porphyrias. Activation of the exquisitely delicate heme […]